Multiple Myeloma (Cancer) – Symptoms and Treatment

Definition of Multiple Myeloma A cancer of the bone marrow in which plasma cells, also called myeloma cells or myelocytes, proliferate, accumulating as lesions (growths) to develop within the bone marrow cavities of the bones. The lesions prevent normal functioning of the bone marrow. They also damage bone tissue and weaken the bone structure. Plasma […]

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Myelodysplasia Syndrome – Definition, Symptoms and Treatment

Definition of Myelodysplasia Syndrome Different constellations of symptoms, all arising from dysfunction of the bone marrow and all leading to various cytopenias (low blood cell counts). In myelodysplasia, also called preleukemia, the number of hematopoietic cells within the bone marrow increases but the produced cells are disordered and often released to the blood while they […]

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Myelofibrosis – Definition, Treatment and Symptoms

Definition of Myelofibrosis Myelofibrosis is a chronic, degenerative condition of the bone marrow in which fibrous tissue replaces the red bone marrow.  Researchers do not know what causes myelofibrosis, which typically develops in people between the ages of 50 and 70, but believe it is an autoimmune response from a single defective blood stem cell (called a clonal dysfunction). […]

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Neutropenia – Definition, Causes and Symptoms

Definition of Neutropenia Lower than normal numbers of neutrophils circulating in the blood. Neutrophils are the most abundant of the three subtypes of granulocytes; the granulocyte is a type of leukocyte (white blood cell). Neutropenia, which can be acute or chronic, results in increased susceptibility to bacterial and fungal (yeast) infection. Severe neutropenia can leave the body […]

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Anemia – causes, symptoms and treatment

Definition Anemia A reduced ability of the blood to meet the body’s oxygenation needs arising from either a diminished volume of erythrocytes (red blood cells) in the blood or from reduced hemoglobin content in the erythrocytes. Though the common perception of anemia is that it is itself a health condition, doctors consider anemia an indication […]

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Polycythemia Vera – Definition, Symptoms and Treatment

Definition of Polycythemia Vera A myeloproliferative condition of the blood in which the red bone marrow produces an excessive volume of erythrocytes (red blood cells), platelets, and neutrophils that results in increased cell volume and decreased fluid volume (plasma) in the blood. This myeloproliferation (overproduction by the bone marrow) thickens the blood (hyperviscosity), making it […]

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Disseminated Intravascular Coagulation (DIC)

Definition of Disseminated Intravascular Coagulation and Treatment Disseminated intravascular coagulation (DIC) – a secondary coagulation disorder arising from an imbalance among the clotting factors in the blood. DIC occurs as a result of a significant underlying health condition such as HIV/AIDS, overwhelming infections, or cancer, and as a serious complication in pregnancy. DIC is a symptom rather than a condition. Indications of its […]

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Sickle Cell Disease – Definition, Symptoms and Treatment

Definition of Sickle Cell Disease An inherited genetic disorder of defective hemoglobin, a protein compound erythrocytes (red blood cells) contain that binds with oxygen. Though the primary effect of sickle cell disease, also called sickle cell anemia, is anemia (insufficient oxygen in the blood), the condition also causes significant pain and damage to organs throughout the […]

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Hematoma – Definition and Treatment

Definition of Hematoma Hematoma – Bleeding into the tissues that forms a contained mass. Most superficial hematomas are benign, such as the common hematoma auris, involving the auricle (outer ear) and black eye, involving the orbital tissues surrounding the eye. Such hematomas typically occur as the consequence of blows to the tissues that cause blood vessels to break. As […]

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Thalassemia (alpha/beta) Disease – Symptoms and Treatment

Definition of Thalassemia alpha/beta Disease A genetic disorder of the blood in which the body fails to produce one or more of the proteins necessary for the synthesis of hemoglobin, the protein that enables erythrocytes (red blood cells) to carry oxygen. The consequence is anemia (inadequate oxygen to the cells throughout the body). There are two basic […]

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