Table of Contents
Definition of Bullous Pemphigoid
Bullous Pemphigoid is an autoimmune disorder in which itchy bullae (blisterlike formations) develop on the SKIN. Bullous pemphigoid is more common in people age 50 and older, and typically occurs in those who are 70 or older. The bullae tend to concentrate in areas where there are skin folds, such as the groin and the creases of the elbows and knees.
The skin around the bullae may be red and tender. The condition is self-limiting, which means it will improve on its own. However, the bullae are very uncomfortable; medical intervention targets relieving their discomfort and hastening the condition’s regression and resolution. The doctor will likely biopsy several of the bullae to obtain a definitive diagnosis.
Treatment with topical and oral CORTICOSTEROID MEDICATIONS reduces the IMMUNE RESPONSE and improves symptoms. The B vitamin niacinamide also provides additional relief for some people. The bullae usually heal without scarring. In most people the bullae heal within a few months, though occasionally the course of disease may run several years.