Definition of Cytokines

cytokines definition

A large family of proteins that mediate and regulate the IMMUNE RESPONSE. Leukocytes (white BLOOD cells) produce this proteins. There are more than 100 cytokines, which may act independently or synergistically with others.

Among the actions of cytokines are cell homing and direction (drawing leukocytes to the site of INFECTION or injury), INFLAMMATION response, and stimulation of the numerous molecules that participate in the immune response.

They may act on the cells that produce them (autocrine activity), on cells in proximity to them (paracrine activity), or on cells throughout the body (endocrine activity).

Major Types of Cytokines

MAJOR TYPES
CHEMOKINESCOLONY-STIMULATING FACTORS (CSFS)
ERYTHROPOIETIN (EPO)INTERFERONS
INTERLEUKINSLYMPHOKINES
MONOKINESTUMOR NECROSIS FACTORS (TNFS)

See also ANTIBODYANTIGENCELL-MEDIATED IMMUNITYHISTAMINE; HORMONE; LEUKOCYTELEUKOTRIENES.

Cytokines definition
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