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Gallbladder absorbs about 90 percent of the water in the bile that arrives from the liver, creating concentrated, potent bile. Fats and proteins in the chyme (partly digested food) the STOMACH sends to the DUODENUM trigger the duodenum to release the digestive HORMONE cholecystokinin (CCK).
CCK stimulates the gallbladder to contract, expelling bile into the duodenum to aid with digestion. The most common health conditions are cholelithiasis (gallstones), cholecystitis (INFLAMMATION), and biliary dyskinesia (inadequate contraction) – CANCER also occurs even though is rare.
Please see the overview section “The Gastrointestinal System.”