Table of Contents
Immune Disorders Definition
Chronic conditions of the IMMUNE SYSTEM that affect the IMMUNE RESPONSE and the body’s ability to protect and defend itself against INFECTION. Immune disorders generally result from a deficiency or absence of some component or structure of immune function. Such a deficiency may be primary, which is congenital (present at birth), genetic (inherited), or acquired (develops during life).
People who have had their spleen surgically removed (SPLENECTOMY) also have reduced immune response, which results in increased susceptibility to infection.
|AUTOIMMUNE DISORDERS||COMMON VARIABLE IMMUNE DEFICIENCY (CVID)|
|lgA NEPHROPATHY||IMMUNOGLOBULIN A (IgA)deficiency|
|IgE deficiency||IgM deficiency|
|PARTIAL COMBINED SEVERE COMBINED IMMUNODEFICIENCY (PCID)||IMMUNODEFICIENCY (SCID)|
|TOXIC EPIDERMAL NECROLYSIS||Wegener’s granulomatosis|
Symptoms of Immune disorders
Frequent or chronic infection is the primary symptom of an immune disorder other than HYPERSENSITIVITY REACTION (allergy). BLOOD tests for immunoglobulins and antibodies generally can diagnose immune disorders. Hypersensitivity reactions generate symptoms according to the type of reaction and may include symptoms of ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ALLERGIC DERMATITIS, or ALLERGIC ASTHMA. ALLERGY TESTING is the preferred diagnostic approach for identifying the allergens responsible for hypersensitivity reaction, though often a person knows the cause of an allergy.
Immune disorders Treatment
Immune disorders are generally chronic, which means treatment can improve symptoms but not cure or end the condition. Common medication therapies for immune disorders include ANTIHISTAMINE MEDICATIONS, NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDS), CORTICOSTEROID MEDICATIONS, leukotriene receptor antagonists, MAST CELL stabilizers, and DISEASE-MODIFYING RHEUMATOID DRUGS (DMARDS). The particular medication regimen depends on the immune disorder and the individual’s symptoms.