Mast Cell Definition

Mast Cell – a granulated LEUKOCYTE that resides in tissues throughout the body. When the IMMUNE RESPONSE stimulates mast cells, they release PROSTAGLANDINSHISTAMINE, and other biochemicals from their granules. Mast cells are primarily responsible for the symptoms that are the hallmark of the HYPERSENSITIVITY REACTIONINFLAMMATION, itching, skin rash, coughing, and sneezing.

Mast cells have an abundant presence in the tissues of mucous membranes such as the nose, pulmonary tract (TRACHEA and bronchi), and gastrointestinal tract. Mast cells also infiltrate the connective tissues. They respond to the stimulation of complement factors and to IMMUNOGLOBULIN E (IgE) antibodies.

For further discussion of mast cells within the context of the structures and functions of the immune system, please see the overview section “The Immune System and Allergies.”

See also ANTIBODYCOMPLEMENT CASCADE; COUGH; LIVING WITH ALLERGIESMUCOSA-ASSOCIATED LYMPHOID TISSUE (MALT); SNEEZE.

Mast Cell – Definition and Function
Rate this post

About The Author

Leave a Reply

Your email address will not be published. Required fields are marked *