Charcot-Marie-Tooth (CMT) disease, syndrome – symptoms, treatment

Charcot-Marie-Tooth (CMT) disease – An inherited neuromuscular disorder in which the myelin sheath that covers and protects the PERIPHERAL NERVES deteriorates. The loss of the myelin sheath allows NERVE signals to escape from the nerves before they reach their destinations. CMT is the most common inherited neuromuscular disorder in the United States, affecting about 150,000 Americans. […]

Read More

Hip Fracture in Older Adults

Hip Fracture in Older Adults- An injury, often preventable, that often results in significant disability or premature death. One in four hip fractures in adults over age 50 results in limited mobility after HEALING; one in four is fatal. Hip FRACTURE becomes a risk with increasing age for a combination of factors that include increasing loss of BONE and MUSCLE mass resulting in […]

Read More

Myopathy – muscle weakness – definition and treatment

Myopathy – MUSCLE weakness that occurs when muscle cells do not function properly. There are numerous forms of myopathy, many of which are congenital (present at birth) or genetic (the result of inherited GENE mutations). Some myopathies are progressive (become worse with time) and others remain stable. Metabolic disorders, HIV/AIDS, IMMUNE DISORDERS, and ADVERSE REACTION to drugs (including ALCOHOL) […]

Read More

Polydactyly – extra fingers or toes

Polydactyly is extra fingers or toes. Polydactyly may occur spontaneously and isolated (without apparent cause) or in conjunction with GENETIC DISORDERS such as PATAU’S SYNDROME (trisomy 13). Most often the extra digit is on the little finger or little toe side of the hand or foot, respectively, and is so rudimentary as to be functionless. Nearly always the […]

Read More

Syndactyly – definition and treatment

Syndactyly – Fingers or toes that are fused together by connective tissue. Sometimes the fusion is only SKIN (simple syndactyly) and other times the fusion involves MUSCLE, ligaments, and BONE (complex syndactyly). Syndactyly is present at birth and often indicates a genetic disorder with additional symptoms. Most commonly the fusion involves the third and fourth fingers […]

Read More