Transforming growth factors (TGFs)
What is Transforming growth factors
CYTOKINES in the BLOOD circulation that attach to the surfaces of cell membranes. Transforming growth factor alpha (TGF-alpha) stimulates the cells to grow, divide, and differentiate (cell proliferation). Lymphocytes and macrophages produce TGF-alpha. TGF-beta stimulates interleukin 1 (IL-1) production and blocks the response of lymphocytes in the inflammatory process. Lymphocytes, macrophages, and platelets secrete TGFs.
See also INFLAMMATION; INTERFERONS; INTERLEUKINS; LYMPHOCYTE; MACROPHAGE; PLATELET; TUMOR NECROSIS FACTORS (TNFS).
